30 Sai no Hoken Taiiku: If you like B Cup H Kei, then you will like this similar story about a 30 year old Virgin man who got help from a love spirit and trying all ways just to break his "cherry!"
A-Channel: Based on the 4-Koma manga, it is the story of 4 girls with weird personalities, if you like slice of life anime, then this is it.
Ao no Exorcist: Taking over from Star Driver's time slot, Okumaru Rin found out he is the son of Satan and a human woman. After his guardian died, every exorcist is trying to kill him. Rin took upon himself and train to be an Exorcist so as to redeem himself.
Appleseed XIII: If you like the CG movies and the 80s anime version, get ready for an update of the hit series which is the retelling of Appleseed.
Hidan no Aria: Tooyama Kinji was enrolled into a special high school that trained criminal investigators and he met Kanzaki H. Aria, a young girl who used dual pistols who is the top detective in the Assault Unit.
Yondemasu yo, Azazel-san: If you like Level E's crazy humor, this one for you!
Bakugan Battle Brawlers Gundalian Invaders: After two seasons, I still don't understand the rules!
C: The Money of Soul and Possibility Control: If you like the Movie "Wall Street" and the Hong Kong Drama Series "The Greed of Man", you will like this show about Finance and Stock Markets.
Denpa Onna to Seishun Otoko: A girl named Touwa Erio claimed that Earth is being targeted by aliens and her cousin, Niwa Makoto soon discovered that Erio has amnesia for a year and was found wandering in the ocean. Remind me of some X-Files episode that I watch before...
Dog Days: From the people who gave you Mahou Shoujou Lyrical Nanoha Series, Princess Millhiore summoned a legendary hero to help her battle the Lion Domain of Garrett. She got Izumi Shinku, a middle school student who love circus action and very athletic to help her. Didn't I see this from Zero no Tsukaima?
Dororon Enma-kun Meeramera: From Go Nagai, the guy who gave you Mazinger Z, Devilman and Cutey Honey come another remake of his classic series. Expect over the top characters and nudity included.
Deadman Wonderland: Ganta was framed for the massacre of his classmates and sentenced to a prison called Deadman Wonderland which the killer known as the "Red Man" is in too. Ganta now began a fight for his survival in the madhouse.
Fireball Charming: Not sure what is it but I swore that character is from the Figma Series.
Gintama: The continuation of the next season. For those who are not sure, it is about Aliens who co-exist with human in Japan during the Edo Era. Gintoki who is a former samurai now doing odd jobs with his sidekicks, Shinpachi and Kagura. This show also have many parodies and pop culture reference which I laugh alot back then.
Hanasaku Iroha: A heartbroken Matsumae Ohana left the city life to stay with her grandmother's Taisho Era Spring Inn. She meet several staff members of the Inn to begin her life as a waitress in this self-discovery series.
Hen Zemi: Matsutaka Nanako join in a strange club called Hen Zemi after having a crush on a guy, Musashi Komugi. However the club is filled with weirdos and their club make reports of perverted actions like urinating and masturbating. If you like MM and Seitoka Yakuindomo's perverted jokes then this show is for you.
Hoshizora e Kakaru Hashi: If you remember Akane-Iro ni Somaru Saku, then this is the next chapter from the same Ero game maker, Fong. Hoshino Kazuma who is suffering from an illness went to the countryside to recover. He lost his way and meet a girl, Nakatsugawa Ui and by accident, kiss her while being discovered by Ui's close friend, Hinata. Somehow, this all look too familiar...
Jewelpet Sunshine: Somehow I have no idea about this show other than it is based the Jewel Pet toyline in Japan.
Kami nomi zo Shiru Sekai II: Translate to "The World God Only Knows" After the first season ended three months ago, I went to buy the manga and enjoy it alot! Basically Kamiya or Kami Sama had a contract with a cute demon girl named Elsie and his mission is to find evil spirits who are in girls' heart. Using his knowledge of Bishoujou games, he try to apply it to the real world with hilarious and unexpected results. Now with new character, Haqua. a fellow demon girl, Kamiya will continue to do what he do best as the world god only knows.
Lotte no Omocha!: Astarotte Ygvar, a young succubus began her plan of a harem as she need the semen of men to survive. However her first male was a butler named Touhara Naoya who is a respectable single father with a ten year old daughter.
Maria Holic Alive: The sequel to the first one two years ago. The pervert skirt dressing, Shindou Mariya continue her torment on fellow room mate, Miyamae Kanako who has a fear of men and will break rashes if in contact.
Metal Fight Beyblade 4D: For hardcore beyblade fans only!
Nichijou: If you like slice of life comedy like Azumanga Daioh, you will enjoy this and episode zero is already out somewhere...
Ore-tachi ni Tsubasa wa Nai: From Navel, the people who brought Shuffle, come another love story in which three group of people's lives were intertwined in the city. If you love Kimikiss or Amagami, get ready for some complicated relationships.
Pretty Rhythm Aurora Dream: Based on the dancing arcade game of the same name which Harune Aira begin her career as an Super Idol and compete with fellow Idols. Expected a lot of bitching around like America's Next Top Model.
Seikon no Qwaser II: When the first season was out, the response was WTF!? Sucking girls breast milk to gain power is really a perverted way which probably exist in Hentai Animes. However it is based on the Virgin Mary feeding breast milk to an infant Jesus. The story continue from where the last season end as Qwaser went undercover as a female student in an all girls school. Watch the uncensored version if you can as the censored one is really unwatchable.
Sengoku Otome ~Momoiro Paradox~: If you like how Japan mix Moe with historical characters then this is for you. Based on the pachinko game of the same name. Famous characters like Oda Nobunaga and Akechi Mitsuhide are female characters and a present day girl named Hide Yoshino came to their time to take the role of Toyotomi Hideyoshio.
SKET DANCE: From Shouen Jump and won Shogakukan Manga Award 2009, it trailed Fujisaki Yusuke, a.k.a. Bossun and his friends as they go about helping fellow students and in conflict with the school council.
Softenni: If you add Prince of Tennis and Bamboo Blade, this is the results! An all female team of Tennis Players who want to work their way to the Nationals!
STEINS;GATE: Spin off from Chaos Head, this story take place in Akihabara. Okabe Rintarou created a microwave signal that can send messages to the past. However a mysterious organisation named SERN want his creation and thus began the cat and mouse game.
TIGER & BUNNY: From Sunrise come an original story about Wanna Be Superheroes trying to do good in the city. (If I want that, I read the Watchmen.)
Toriko: When I read the manga, the first thing that came in my head was Monster Hunter on Steroids. From Shouen Jump, come Toriko, a gourmet hunter who hunt outrageous creatures and cook them for food! If you like cooking shows like "Mr Aijiko" and playing Monster Hunter, get ready for Hell's Kitchen.
X-Men: After Wolverine, why not follow up with X-Men? Not only that, the team which comprises of Wolverine, Cyclops, Storm and Beast are in Japan searching for missing fellow mutant "Armor" and battling a cult known as U-Men. Do you think too many X-Men is bad for you?
Yu-Gi-Oh ZEXAL: Seriously, how many spin-off of Yu-Gi-Oh do they want to make anyway?
There are some shows that I didn't mention like BL anime Sekai Ichi no Hatsukoi, Gambling Anime, Gyakkyou Burai Kaiji Hakairoku-hen which is not my cup of tea.
Well, what will it be for this season? X-Men look ok, Dog Days despite having a similar story like Zero no Tsukaima but I will watch it as Horie Yui and Miyano Mamoru are playing the main leads. The World God only Knows is a YES for me. Ao no Exorcist looks promising with two of my favourite male seiyuus, Okamoto Nobuhiko and Fukuyama Jun in it. The rest of the shows will be a "Watch for the first three episodes" then confirm.
Edit on 27/03/11:
Moshidora: Kawashima Minami help her friend, Miyata Yuuki who is sick to manage the male's baseball team in her school. However the baseball team is a weak team until Minami found a management book wrote by real life Socialist Peter Drucker and used his teachings to turn the team around!